- A. Underactive
- B. Overactive ✓
- C. Inactive
- D. None of the above
Systemic lupus erythematosus (SLE) is an autoimmune disease where the immune system mistakenly attacks healthy tissues in various parts of the body. This overactivity of the immune system leads to inflammation, tissue damage, and a range of symptoms affecting different organs and systems.
Patients with systemic lupus erythematosus (SLE) have an overactive immune system characterized by polyclonal B-cell hyperreactivity. This overactivity leads to various abnormalities in B-cell activation, differentiation, and selection processes, contributing to the development of autoimmunity in SLE. The immune system in SLE is not underactive, inactive, or normal but rather exhibits heightened reactivity and dysregulation.
