- A. Ureaplasma urealyticum ✓
- B. Fusobacterium nucleatum
- C. Mycoplasma hominis
- D. Escherichia coli
- E. Group B Streptococcus
In cases of preterm premature rupture of membranes (PROM), the most common microorganism isolated by culture of amniotic fluid is Ureaplasma urealyticum. This bacterium is a common cause of intrauterine infection and has been associated with adverse pregnancy outcomes, including preterm birth.
Ureaplasma urealyticum is a part of the normal genital flora in some individuals but can lead to infections when it ascends into the upper genital tract, such as the amniotic cavity in pregnant women with PROM. In cases of preterm PROM, identifying the causative microorganism through amniotic fluid culture is crucial for appropriate management and treatment to prevent complications for both the mother and the fetus.
In other words, Ureaplasma urealyticum is a bacterium that belongs to the class Mollicutes and is commonly found in the genitourinary tract. It has been associated with various adverse pregnancy outcomes, including preterm PROM. Studies have shown that Ureaplasma urealyticum is frequently isolated from the amniotic fluid of women with preterm PROM, indicating its role in ascending intrauterine infections.
While other microorganisms like Fusobacterium nucleatum, Mycoplasma hominis, Escherichia coli, and Group B Streptococcus can also be isolated from amniotic fluid cultures in cases of preterm PROM, Ureaplasma urealyticum stands out as the most common pathogen in this scenario.
Therefore, in the context of preterm PROM and culture of amniotic fluid, Ureaplasma urealyticum is the most frequently isolated microorganism.
